Sep 24, 2023
CHM 133 - Survey of Organic Chemistry
Fundamental treatment of organic chemistry, nomenclature, properties of selected functional groups, mechanisms, stereochemistry and synthetic methods.
Prerequisites: CHM 145 General Chemistry I and CHM 145L General Chemistry I Laboratory
Corequisites: CHM 133L Survey of Organic Chemistry Laboratory and CHM 146 General Chemistry II and CHM 146L General Chemistry II Laboratory
3 Class Hours
Learning Outcomes of the Course:
Upon successful completion of this course the student will be able to:
- Apply the IUPAC rules of nomenclature to alkanes, alkenes, arenes, alkyl halides, alcohols, ethers, phenols, aldehydes, ketones, carboxylic acids, esters, amines, carbohydrates, amino acids, and proteins.
- Draw the structures of the above mentioned compounds given their names.
- Use the cis-trans system or the E,Z sequence rules to classify alkenes.
- Predict the major and minor products of addition and elimination reactions using Markovnikov’s rule and Zaitsev’s rule.
- Identify the major product(s) in electrophilic aromatic substitution reactions.
- Propose synthetic routes to substituted benzenes via multi-step pathways.
- Classify stereoisomers as either enantiomers or diastereomers.
- Predict the predominant reaction pathway as SN1, SN2, E1, or E2.
- Outline synthetic routes to primary, secondary, and tertiary alcohols.
- Explain how the Williamson synthesis is used to prepare ethers.
- Describe the preparation of aldehydes/ketones from alcohols using oxidizing agents.
- Use Grignard reagents in syntheses that convert aldehydes/ketones to alcohols.
- Describe the use of the Fischer esterification reaction to make esters from carboxylic acids.
- Show how an amino group can be attached to an aromatic ring via the reduction of a nitroarene.
- Outline synthetic routes to substituted benzenes via the Sandmeyer reaction.
- Draw and name the cyclic structures of monosaccharides.
- Classify disaccharides and polysaccharides as reducing or nonreducing.
- Draw and name the structures of peptides.
- Determine the structure of a peptide given sequencing data.
Methods of Assessing Outcomes:
The expected learning outcomes will be assess via 8 quizzes and 12 exams.