CHM 246 - Organic Chemistry II
A continuation of CHM 245 Organic Chemistry I including spectroscopy and introduction to molecules of biological importance.
Prerequisite: CHM 245 Organic Chemistry I
Corequisite: CHM 246L Organic Chemistry II Laboratory
3 Class Hours
Learning Outcomes of the Course:
Upon successful completion of this course the student will be able to:
1. Apply IUPAC rules of nomenclature to alcohols, arenes, ethers, phenols, aldehydes, ketones, carboxylic acids, esters, amines, carbohydrates, amino acids, and proteins.
2. Draw the structures of the above mentioned compounds given their names.
3. Outline synthetic routes to primary, secondary, and tertiary alcohols.
4. Show how oxidizing agents can be used to convert alcohols to aldehydes, ketones, and carboxylic acids.
5. Describe the conversion of alcohols to alkanes, alkyl halides, alkenes, ethers, esters, and alkoxides.
6. Use NMR data to propose structures for unknown organic compounds.
7. Explain how the Williamson synthesis is used to prepare ethers.
8. Identify the major product(s) in electrophilic aromatic substitutions.
9. Propose synthetic routes to substituted benzenes via multi-step pathways.
10. Use Grignard reagents in synthetic schemes that convert aldehydes and ketones to alcohols.
11. Describe the use of the Fischer esterification reaction to make esters from carboxylic acids.
12. Show how an amino group can be attached to an aromatic ring via the reduction of a nitroarene.
13. Devise synthetic routes to substituted arenes via the Sandmeyer reaction.
14. Draw and name the cyclic structures of monosaccharides.
15. Classify disaccharides and polysaccharides as reducing or nonreducing.
16. Draw and name the structures of peptides.
17. Determine the structure of a peptide given sequencing data.
Methods of Assessing Outcomes:
The expected learning outcomes will be assessed via 8 quizzes and 12 exams.
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