Jul 08, 2020
BIO 216 - Immunology
An introduction to the basic concepts in immunology, including development of the immune system, innate immunity, immunoglobulin structure and genetics, antigen-antibody reactions, the major histocompatibility complex and antigen presentation, T cell receptors, T cell activation and effector functions, energy and apoptosis, adhesion molecules, phagocytic cell function, immune responses to infections organisms and tumors, autoimmune diseases, allergies, immune deficiencies and AIDS.
Prerequisites: BIO 131 Human Biology I, BIO 131L Human Biology I Laboratory and BIO 132 Human Biology II, BIO 132L Human Biology II Laboratory
MLT 216 and CLT 216
3 Class Hours
Learning Outcomes of the Course:
Upon successful completion of this course the student will be able to:
- List the elements of the immune system and describe their roles in defense.
- Describe the structure of immunoglobulins and discuss the mechanism for generation of antibody diversity.
- Discuss the nature of antigens and the characteristics that contribute to immunogenicity.
- Describe in detail, the normal and abnormal functions of the human immune response, including antigen recognition by T lymphocytes, development of T and B cells, T cell-mediated immunity, immunity mediated by B cells and antibodies, innate immunity, and the complement system.
- Explain the mechanisms and pathogenesis of disorders of the immune system, including immunodeficiencies, hypersensitivities, autoimmune disorders, and immunoproliferative abnormalities.
- Describe clinical implications of the immune response such as immunization, transplant rejection, tumor immunity, and the immunity of pregnancy.
- Evaluate clinical cases to apply information to assess diagnoses, symptoms, etiology, prognosis, possible treatments, and other case-related information.
- Describe the lab tests performed used to assess immune function and status, and propose and evaluate the clinical significance of appropriate laboratory testing results.
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