CLT 216 - Immunology
An introduction to the basic concepts in immunology, including development of the immune system, innate immunity, immunoglobulin structure and genetics, antigen-antibody reactions, the major histocompatibility complex and antigen presentation, T cell receptors, T cell activation and effector functions, anergy and apoptosis, adhesion molecules, phagocytic cell function, immune responses to infections organisms and tumors, autoimmune diseases, allergies, immune deficiencies and AIDS.
Prerequisites: BIO 131 Human Biology I and BIO 132 Human Biology II
BIO 216 and MLT 216
3 Class Hours
Learning Outcomes of the Course:
Upon successful completion of this course the student will be able to:
1. List the elements of the immune system and describe their roles in defense.
2. Describe the structure of immunoglobulins and discuss the mechanism for generation of antibody diversity.
3. Discuss the nature of antigens and the characteristics that contribute to immunogenicity.
4. Describe, in detail, the normal and abnormal functions of the human immune response, including antigen recognition by T cell lymphocytes, development of T and B cells, T cell-mediated immunity, immunity mediated by B cells and antibodies, innate immunity and the complement system.
5. Explain the mechanisms and pathogenesis of disorders of the immune system, including immunodeficiencies, hypersensitivities, autoimmune disorders, and immunoproliferative abnormalities.
6. Describe clinical implications of the immune response such as immunization, transplant rejection, tumor immunity, and the immunity of pregnancy.
7. Evaluate clinical cases to apply information to assess diagnoses, symptoms, etiology, prognosis, possible treatments, and other case-related information.
8. Describe the lab tests used to assess immune function and status, and propose and evaluate clinical significance of appropriate laboratory testing results.
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