CLT 206 - Immunohematology
An introduction to the field of blood banking, including the study of theoretical knowledge of blood groups and blood grouping, component and transfusion therapies, transfusion reactions, and allo- and auto-antibody formation. In laboratory sessions, the student performs ABO and Rh grouping, antibody identification, and compatibility testing.
Prerequisite: CLT 216 Immunology or BIO 216 Immunology, and approval of the CLT advisor
2 Class Hours, 2 Laboratory Hours
Learning Outcomes of the Course:
Upon successful completion of this course the student will be able to:
1. Follow proper safety guidelines in the laboratory at all times.
2. Display appropriate professional behavior.
3. Demonstrate logical approaches to problem solving - selecting appropriate units and crossmatching them with unknown patient specimens.
4. Describe classic problems inherent to blood transfusion and the solutions currently in use.
5. Apply basic principles of genetics to immunohematology.
6. Apply basic principles of immunology to blood group serology.
7. Describe and perform the testing procedures performed in the clinical immunohematology laboratory, including Coombs’ (antiglobulin) testing, ABO testing, Rh testing, other blood group testing, alloantibody screening, elutions, RBC autoantibody testing, compatibility testing, and traditional and gel technology.
8. Explain the process of donor selection, describe the processes of blood or blood component donation, including apheresis.
9. Explain the clinical significance of abnormal and disease states related to immunohematology, including drug-induced red blood cell destruction, polyagglutination, transfusion reactions, and Hemolytic Disease of the Newborn (HDN) and list the procedures relevant to each.
10. Describe and perform transfusion test procedures, including procedures related to component therapy.
11. Discuss medicolegal aspects of bloodbanking and the medicolegal responsibilities of a immunohematologist.
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